Which of the following is NOT TRUE about Shotgun Sequencing?
A、When DNA fragments derived from different chromosomal regions have repeats of the same sequence, they will appear to overlap
B、When DNA fragments derived from different chromosomal regions have repeats of the same sequence, they should be from the same gene locus.
C、In a new whole shotgun approach, Celera Genomics is sequencing both ends of DNA fragments of short (2 kb), medium (10 kb), and long (BAC or >100 kb) lengths
D、A large number of reads are then assembled by computer