Which of the following is TRUE about DNA sequencing methods?
A、Taq polymerase is quite heat sensitive
B、Purified fragments of DNA cut from plasmid or amplified by polymerase chain reaction (PCR)
C、Clones of DNA fragments are denatured to single strands, and one of the strands is hybridized to an oligonucleotide primer
D、New strands of DNA are synthesized from the end of the primer