Supposing passive transport of nonionized forms of the following drugs determines the rate
A、Aspirin, weak acid (pKa = 3.0)
B、Ethacrynic acid, weak acid (pKa = 3.5)
C、Sulfamethoxazole, weak acid(pKa=5.6)
D、Secobarbital, weak acid (pKa = 7.8)
E、Theophylline, weak base (pKa = 8.8)