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提问人：网友lin52005 发布时间：2022-01-07

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【单选题】A patient presents in your office with very high levels of serum cholesterol. Afte

r a series of tests, you conclude that the patient has high circulating levels of LDL cholesterol, but has normal levels of the liver LDL receptor. One possible explanation for this observation is which of the following？

A、The patient has a mutated form of apoprotein B-100.

B、The inability to selectively remove cholesterol from the LDL complex.

C、The absence of the enzyme lipoprotein lipase.

D、Decreased levels of acyl-CoA: cholesterol acyltransferase

E、Altered phosphorylation of the LDL receptor.

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更多“【单选题】A patient presents in your office with very high levels of serum cholesterol. Afte”相关的问题

第1题

【单选题】拼小版时页面三要素为（）

A、图像、文字、表格

B、图像、图形、文字

C、文字、线条、图形

D、图像、文字、线条

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第2题

【单选题】下列说法错误的是（）

A、企业年金是指企业及其职工在依法参加基本养老保险的基础上,自愿建立的补充养老保险。

B、企业年金不能代替职工的基本养老保险,

C、企业年金是企业年底给职工发的奖金。

D、企业年金是国家为建立多层次的养老保险制度、更好地保障职工退休后的生活而建立的补充养老保险。

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第3题

After they are produced from acetyl-CoA in the liver, ketone bodies are mainly used for which one of the following processes?

A、Excretion as waste products.

B、Energy generation in the liver.

C、Conversion to fatty acids for storage of energy.

D、Generation of energy in the tissues.

E、Generation of energy in red blood cells.

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第4题

Which is the following can transfer acetyl group from mitochondria to cytoplasm

A、Acetyl-CoA

B、Acetyl-carnitine

C、Succinate

D、Citric acid

E、Oxaloacetate

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第5题

The class of drugs called statins have proved very effective against hypercholesterolemia, a major cause of atherosclerosis and associated cardiovascular disease. These drugs reduce plasma cholesterol levels by:

A、Preventing absorption of cholesterol from the intestine.

B、Increasing the excretion of cholesterol from the body via conversion to bile acids.

C、Inhibiting the conversion of 3-hydroxy-3-methylglutaryl-CoA to mevalonate in the pathway for cholesterol biosynthesis.

D、Increasing the rate of degradation of 3-hydroxy-3-methylglutaryl CoA reductase.

E、Stimulating the activity of the LDL receptor in the liver.

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第6题

Under condition of starvation, the major fuel for the brain is

A、blood glucose

B、fatty acids

C、ketone bodies

D、amino acids

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第7题

The rate-limting enzyme in the β-oxidation of fatty acid is

A、acyl CoA synthetase

B、carnitine acyltransferase I

C、carnitine acyltransferase II

D、acyl CoA dehydrogenase

E、hydroxyacyl CoA dehydrogenase

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第8题

The subcellular site of the breakdown of long chain fatty acids to acetyl-CoA via -oxidation is:

A、The cytosol

B、The matrix of the mitochondria

C、The endoplasmic reticulum

D、The mitochondrial intermembrane space

E、E.The Golgi apparatus

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第9题

【单选题】A 19-year-old man complains of “brown urine” and pain in the muscles of his arms and legs experienced while playing touch football. He has had several episodes of muscle pain during exercise, but he had not noticed darkening of his urine afterward. The pain usually resolved overnight. Physical examination reveals a well-fed male of normal stature. Reflexes and range of motion in all arms and legs are normal, but there is some paraparesis (weakness), especially in his right leg. A muscle biopsy is taken and sent for specialized resting. The patient is sent home with a recommendation to take a dietary carnitine supplement. Which of the following is the most likely diagnosis?

A、Medium-chain fatty acyl CoA dehydrogenase (MCAD) deficiency

B、Carnitine deficiency

C、Carnitine palmitoyltransferases I deficiency

D、Carnitine palmitoyltransferases II deficiency

E、Marfan syndrome

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第10题

In humans, obesity is not caused by leptin levels, but by malfunctioning signal mechanisms. Which of the following do you think might be affected by high leptin concentrations binding to receptor?

A、Activation of acetyl CoA to malonyl CoA

B、Lipase

C、Phosphate pentose pathway

D、Cholesterol synthesis

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