4. Lisa has three .
A.A. brother-in -law
B.B. brothers-in-law
C.C brother-in-laws
D.D. brothers-in-laws
- · 有6位网友选择 C,占比54.55%
- · 有2位网友选择 B,占比18.18%
- · 有2位网友选择 A,占比18.18%
- · 有1位网友选择 D,占比9.09%
A.A. brother-in -law
B.B. brothers-in-law
C.C brother-in-laws
D.D. brothers-in-laws
To the joy of the parents,their only son is now ________ to achieve his goal. |
[ ] |
A.making every effort B.making all effort C.make an effort D.sparing no efforts |
Abstract Anticancer agents are critical for the cancer treatment, but side effects and the drug resistance associated with the currently used anticancer agents create an urgent need to explore novel drugs with low side effects and high efficacy. 1,2,3-Triazole is privileged building block in the discovery of new anticancer agents, and some of its derivatives have already been applied in clinics or under clinical trials for fighting against cancers. Hybrid molecules occupy an important position in cancer control, and hybridization of 1,2,3-triazole framework with other anticancer pharmacophores may provide valuable therapeutic intervention for the treatment of cancer, especially drug-resistant cancer. This review emphasizes the recent advances in 1,2,3-triazole-containing hybrids with anticancer potential, covering articles published between 2015 and 2019, and the structure-activity relationships, together with mechanisms of action are also discussed.
In 1819, the same year that Louis entered the Institution, Charles Barbier, an army captain, reported to the Academy of Sciences on a system of raised dots and dashes which enabled soldiers to read messages in the dark.Later, Barbier brought his invention to the Institution.After experimenting with it, young Braille produced a writing system using only dots, from which he gradually devised 63 separate combinations representing the letters in the French alphabet.At the request of an Englishman, he later added the letter “w”, accents and punctuation marks, and mathematical signs.Although government bureaucracy prevented immediate official adoption, his system was used at the Institution as long as the director, Dr.Pignier, was in office.Pignier’s successor insisted on returning to the officially approved former system, but students continued to use Braille's method secretly.Eventually, its superiority was established and it was adopted throughout France.
(1).Louis-Braille first learned to read with the aid of _________________.
A.his father
B.special books at the Institution
C.the village school teacher
D.Captain Barbier's system of dots and dashes
(2).Louis's father kept him at the village school until he was ten because his father ________________.
A.wanted Louis to help him in the harness shop
B.thought it was not worthwhile to have Louis work when he was young
C.did not want Louis to live the same sort of life as that of other blind people
D.wanted Louis to remain with the family as long as possible
(3).Louis Braille did all of the following things EXCEPT________________.
A.teaching young children at the Institution
B.developing a writing system for the blind
C.learning to play musical instruments well
D.encouraging students to use his method secretly
(4).Charles Barbier originally devised his writing system for________________.
A.the Academy of Sciences
B.blind children
C.military personnel
D.the English government
(5).Braille's method was not adopted officially for some time because________________.
A.the students preferred the former method
B.the large library collection would then have been useless
C.Dr.Pignier's successor disliked Braille's method
D.the government was slow to approve it
A、A. yours brother
B、B. your brothers'
C、C. your brother's
D、D. your brother
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