The strands of the DNA molecule are antiparallel, which means that ().
A、both strands are oriented in a 5' to 3' direction
B、both strands are oriented in a 3' to 5' direction
C、the molecule is oriented differently from the rest of the cell
D、only one strand of the molecule replicates
E、one strand is oriented in a 5' to 3' direction and the other in a 3' to 5' direction